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Acting on theosteoblast, PTH induces a factor ‘Receptor foractivation of nuclear factor- B-ligand’ (RANKL)which diffuses and combines with RANK onosteoclast precursors and transforms them intoosteoclasts as well as activates osteoclasts (Fig.24.2). Inaddition, without cAMP Tregs are unable to induce anergy in responding/effector T cells byits injection. [52] reviewed nine cases withtuberculous pubic arthritis published during the last three decades

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